On the afternoon of February 22nd, at the press conference of epidemic prevention and control in novel coronavirus, Zhejiang Province, Song Zhiheng, Deputy Secretary of the Party Group and Deputy Director of the Provincial Science and Technology Department, introduced the progress of vaccine research and development in Zhejiang Province.
Song Zhiheng said that the Provincial Department of Science and Technology supported the cooperation between the Provincial Center for Disease Control and Prevention, the First Hospital of Zhejiang University, Hangzhou Medical College and other enterprises, and carried out research and development routes of inactivated vaccine, recombinant protein vaccine, adenovirus vector vaccine, mRNA vaccine and other technologies in parallel, and continued to promote key links such as virus strain isolation, process improvement and animal experiments. These studies have made good progress.
Song Zhiheng introduced that in the research of recombinant protein vaccine, antibodies have been produced by the first batch of pre-experimental mice; The research and development of mRNA vaccine has entered the stage of animal experiment. The research and development of recombinant adenovirus vector vaccine, the amplification and culture of recombinant virus, and animal experiments will be carried out in the near future; The research and development of inactivated vaccine has screened the fourth generation vaccine strain. At present, researchers are racing against time to overcome problems. However, we should also be soberly aware that due to the long period of vaccine research and development, we must respect scientific laws and go through a scientific, rigorous and safe research process.
In addition, Song Zhiheng introduced that Zhejiang Province has made a major breakthrough in the field of basic research in Covid-19, and the Zhejiang Structural Biology Laboratory of West Lake University successfully analyzed the full-length structure of Covid-19 receptor-ACE2 by using cryoelectron microscopy. Yesterday morning, West Lake University released scientific research results again, and analyzed the composite structure of full-length ACE2 and Covid-19 S protein receptor binding domain, which played an important role in finding and optimizing inhibitors that blocked coronavirus from entering cells.
(Source: Tianmu News)