On the afternoon of February 22, the 27th press conference on the prevention and control of novel coronavirus pneumonia epidemic in Zhejiang province was held in Hangzhou. Zhejiang Provincial Science and Technology Department Deputy Secretary of the Party Group, Deputy director Song Zhiheng attended the press conference and answered reporters’ questions.
ask a question:
After the outbreak of the epidemic, Zhejiang immediately organized an emergency scientific and technological breakthrough. What progress has been made in these key projects?
Since the outbreak, to in accordance with the “focus, emergency first, achievement oriented, strengthen as a whole” principle, the provincial department successively in the virus, the spread of the virus, comprehensive treatment system, rapid detection, suit the medicine, vaccine development, treatment of traditional Chinese medicine, etc., start two batches of six categories of COVID-19 emergency scientific research projects and four emergency natural science fund special, form province COVID-19 epidemic control emergency scientific research panel, concentrated strength, joint research, to win the epidemic prevention and control war provide scientific and technological support.
In terms of comprehensive treatment
The provincial Department of Science and Technology gave full support to the key projects. Based on the repeated verification and improvement of antiviral drug treatment, artificial liver treatment, microecological regulation and other aspects, the first Hospital of Zhejiang University has added nutritional support, psychological intervention and other treatment and intervention means, and specially set up the care content for severe patients, forming the diagnosis and treatment experience of COVID-19 in Zhejiang, providing reference for the treatment of the whole province and the whole country.
Organization of Zhejiang province hospital, provincial tongde hospital led to carry out prevention and traditional Chinese and western medicine treatment of special research, preliminary results show that to shorten treatment of traditional Chinese medicine, speed up the recovery has obvious advantages, have good effect on severe turn mild, seven kinds of Chinese medicine prescription, has been approved by the department for hospital preparations.
In the research and development of diagnostic reagents
Focusing on how to shorten the detection time and improve the detection accuracy, the project of “Novel Coronavirus rapid diagnosis technology and reagent research and development” has been implemented. The team of Hangzhou Medical College has developed the COVID-19 virus nucleic acid diagnostic kit and antibody detection reagent, which have been registered in the European Union. The next step will be put into production and used to fight COVID-19. In particular, Zhejiang Provincial Center for Disease Control and Prevention, the First Hospital of Zhejiang University and the First Affiliated Hospital of Wenzhou Medical University have launched close cooperation with Hangzhou Usstar Biotechnology Co., Ltd., Ltd., and the rapid testing products are actively striving to enter the emergency approval channel of the State Food and Drug Administration.
In terms of vaccine research and development
Support the provincial Center for Disease Control and Prevention, the First Hospital of Zhejiang University, Hangzhou Medical College (Provincial Medical Institute) and other enterprises to carry out the research and development routes of inactivated vaccine, recombinant protein vaccine, adenovirus vector vaccine and mRNA vaccine, and continue to promote key links such as strain isolation, process improvement and animal experiments.
These studies have made good progress:
● Research of recombinant protein vaccine, after the first batch of pre-experimental mice tested, have produced antibodies; mRNA vaccine development has entered the animal experimental stage;
● Development of a recombinant adenovirus vector vaccine, and the expansion of the recombinant virus began.Additional culture, animal experiments will be carried out in the near future;
● Inactivated vaccine development, has been screened to the fourth generation of vaccine strains.
At present, researchers are racing against time to overcome difficult problems. However, we should also be soberly aware that because the vaccine development cycle is relatively long, we must respect the scientific laws and go through a scientific, rigorous and safe research process.
In addition, Zhejiang has made a major breakthrough in the field of novel coronavirus basic research. The full-length structure of novel coronavirus receptor —— ACE 2 was successfully solved by cryoEM technology. In the early morning of yesterday morning, Westlake University has released scientific research results again, analyzing the composite structure of full-length ACE 2 and the receptor binding domain of novel coronavirus S protein, which has played an important role in the discovery and optimization of inhibitors that block the entry of coronavirus into cells, and further boosted our confidence in defeating the virus and the epidemic.
ask a question:
The epidemic has had a certain impact on the development of Zhejiang. How can the science and technology departments serve the resumption of work and production of enterprises, especially to reduce the impact of the epidemic through scientific and technological innovation?
Since the outbreak of the epidemic, in accordance with the unified deployment of the provincial Party Committee and the provincial government, the “eight measures” for benefiting enterprises have been introduced to fully support the resumption of work and production of science and technology enterprises, fight against the epidemic and promote development.
For example, reducing rent for 2 months, increasing the use of innovation vouchers from 200,000 to 500,000, and free opening of large scientific instruments and equipment to promote sharing, further reduce the cost of innovation; fully implement “zero run” and “online office”, open convenient service channels for scientific and technological talents, and provide free online technical services.
Eight service lists have been set up to further promote the implementation of the policies. Focus around greatly affected by the outbreak of all kinds of innovation main body, combing the province key research and development projects, high-tech industry investment projects, high-tech enterprises, technology-based small and medium-sized enterprises, business incubators (the space), industrial innovation service complex, new research and development institutions, credit key support enterprise eight service list, and carry out the “one to one” service.
At present, more than 120 science and technology business incubators (mass innovation space) in the province have been promoted to reduce rent for incubated enterprises; the credit support list of more than 100 key COVID-19 emergency research projects or undertake key tasks of COVID-19 prevention and control has been reported to the Ministry of Science and Technology for loan discount interest and interest support; specially compiled anti-epidemic production guidance manual to help agricultural science and technology enterprises to resume production as soon as possible.
At the same time, the implementation of the “double hundred” special action to deepen the “three services”, set up 116 service groups in provinces, cities and counties, 5 party members service pioneers and more than 450 science and technology commissioners, to implement the policy of affordable enterprises and warm enterprises, service emergency research, and promote the orderly and efficient resumption of work and production of enterprises.
The next step, will be according to the provincial party committee requirements, in the.Combine standards with long-term development, and pay more attention to the coordination and unification of policies and measures, focusing on increasing investment in RESEARCH and development, strengthening classified guidance, and promoting financial and credit support, so as to minimize the impact of the epidemic with the acceleration of scientific and technological innovation.
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